Author

S. H. Tsang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. G. Bassuk· 1 shared B. M. Robbings· 1 shared C. A. Doege· 1 shared C. A. Leduc· 1 shared C. M. Bisbach· 1 shared D. Egli· 1 shared D. J. Williams· 1 shared D. T. Hass· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. G. Bassuk

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4 papers

Recent·Most cited

In vivo exchange of glucose and lactate between photoreceptors and the retinal pigment epithelium

D. T. Hass, E. Giering, J. Y. S. Han, C. M. Bisbach, K. Pandey, B. M. Robbings, T. O. Mundinger, N. D. Nolan, S. H. Tsang, N. J. Philp, N. S. Peachey, J. B. Hurley

The paper demonstrates that photoreceptors supply lactate to the RPE, supporting a metabolic exchange between these retinal cells.

bioRxiv · Apr 10, 2023 · PreprintBiochemistry

Regulation of intracellular signaling and neuron function by Bardet-Biedl Syndrome proteins in patient-specific iPSC-derived neurons

L. Wang, Y. Liu, G. Stratigopoulos, S. Panigrahi, L. Sui, C. A. Leduc, H. J. Glover, M. C. De Rosa, L. C. Burnett, D. J. Williams, L. Shang, R. Goland, S. H. Tsang, S. Wardlaw, D. Egli, , R. L. Leibel

This study investigates how BBS mutations affect neuron function and signaling in iPSC-derived neurons, identifying impaired ciliary function and signaling pathways related to energy homeostasis.

bioRxiv · Oct 29, 2020Cell Biology

Evidence of Presence and Activation of the two Cell Cycle Kinases Nek6 and Nek7 in the ciliated Neuroretina

K. M. Janisch, J. M. Kasanuki, R. J. Davis, S. H. Tsang

The paper identifies Nek6 and Nek7 expression in retinal tissue and shows their light-dependent activation in photoreceptor outer segments, linking them to phototransduction and outer segment biogenesis.

bioRxiv · Mar 27, 2020 · PreprintBiochemistry

Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration

K. Wert, G. Velez, K. Vijayalakshmi, V. Shankar, J. Sengillo, R. N. Zare, A. G. Bassuk, S. H. Tsang, V. B. Mahajan

The study identifies proteomic and metabolite pathways affected in retinal neurodegeneration and shows that replenishing TCA cycle metabolites provides neuroprotection.

bioRxiv · Sep 10, 2019Biochemistry