A highly active Burkholderia polyketoacyl-CoA thiolase for production of triacetic acid lactone
Z. Wang, S. Cheong, J. H. Pereira, J. Kim, A. DeGiovanni, Y. Guo, G. Lan, C. A. Barcelos, R. Haushalter, T. S. Lee, P. D. Adams, J. D. Keasling
The paper identifies a Burkholderia polyketoacyl-CoA thiolase with significantly higher TAL production activity than 2-PS, achieving 2.8 g/L in E. coli fermentations.
bioRxiv · Dec 4, 2022 · PreprintBioengineering