A. Deutschbauer

High-throughput genetics enables identification of nutrient utilization and accessory energy metabolism genes in a model methanogen

This paper uses high-throughput genetics to identify nutrient utilization and accessory energy metabolism genes in the methanogen Methanococcus maripaludis.

A novel phenylpropanoid methyl esterase enables catabolism of aromatic compounds that inhibit biological nitrification

The paper identifies a novel phenylpropanoid methyl esterase that catabolizes aromatic biological nitrification inhibitors, enabling their use as carbon sources by bacteria.

Sorgoleone degradation by sorghum-associated bacteria; an opportunity for enforcing plant growth promotion

The paper identifies bacterial strains capable of degrading sorgoleone, a plant exudate, and characterizes the genetic basis for this trait, offering potential for engineering beneficial plant-microbe interactions.

A weaponized phage suppresses competitors in historical and modern metapopulations of pathogenic bacteria

The paper identifies a tailocin, a phage-derived element, used by Pseudomonas spp. to suppress competitors in metapopulations, showing its persistence over 170 years.

Construction and characterization of a genome-scale ordered mutant collection of Bacteroides thetaiotaomicron

The paper constructs an ordered mutant collection of Bacteroides thetaiotaomicron using transposon-insertion and barcode sequencing, identifies factors limiting coverage, and demonstrates phenotypic screening for growth defects and cell shape changes.

Systematic dissection of a complex gut bacterial community

This study constructs a defined gut bacterial community of 104 strains and investigates strain-strain and strain-nutrient interactions through amino acid dropout experiments.

Functional analysis of the fatty acid and alcohol metabolism of Pseudomonas putida using RB-TnSeq

This study uses RB-TnSeq to functionally analyze fatty acid and alcohol metabolism in Pseudomonas putida, identifying gene roles and catabolic pathways for isoprenol and isopentanol.

Distinctiveness of genes contributing to growth of Pseudomonas syringae in diverse host plant species

This study identifies genes contributing to Pseudomonas syringae growth in three plant hosts, finding 50 genes with distinct fitness contributions across species.

Iron Supplementation Eliminates Antagonistic Interactions Between Root Associated Bacteria

The paper shows iron supplementation eliminates antagonistic interactions between root-associated bacteria by revealing iron limitation drives these interactions.

Leveraging host metabolism for bisdemethoxycurcumin production in Pseudomonas putida

This study identifies bottlenecks in T3PKS product production in Pseudomonas putida and shows that deleting a catabolic enzyme increases bisdemethoxycurcumin yield.

Large-scale chemical-genetics of the human gut bacterium Bacteroides thetaiotaomicron

This study systematically measures mutant phenotypes for genes in Bacteroides thetaiotaomicron to uncover gene functions and improve understanding of gut microbiota physiology.