Author

R. J. Bryant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. D. Lamb· 2 shared B. Vojnovic· 2 shared C. Verrill· 2 shared D. A. Scheiblin· 2 shared D. A. Wink· 2 shared F. C. Hamdy· 2 shared I. G. Mills· 2 shared S. J. Lockett· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

A. D. Lamb

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features

S. R. Rao, C. Verrill, L. Cerundolo, N. K. Alham, Z. Kaya, M. O'Hanlon, A. Hayes, A. Lambert, M. James, I. D. C. Tullis, J. Niederer, S. Lovell, A. Omer, F. Lopez, T. Leslie, , F. C. Hamdy

This study integrates multi-region whole genome sequencing with histopathological data to reconstruct tumour phylogenies and identify molecular steps in prostate cancer progression and metastasis.

bioRxiv · Feb 27, 2023Cancer Biology

NOS2 and COX2 Blockade Limits TNBC Disease Progression and Alters CD8+ T Cell Spatial Orientation and Density

V. Somasundaram, L. A. Ridnour, R. Y. S. Cheng, A. J. Walke, N. Kedei, D. D. Bhattacharyya, A. L. Wink, E. F. Edmondson, D. Butcher, A. Warner, T. H. Dorsey, D. A. Scheiblin, W. Heinz, R. J. Bryant, R. Kinders, , D. A. Wink

This paper shows that blocking NOS2 and COX2 reduces TNBC tumor growth and improves CD8+ T cell infiltration and spatial distribution in tumors.

bioRxiv · Jun 3, 2022 · PreprintCancer Biology

Tumor irradiation combined with vascular-targeted photodynamic therapy enhances anti-tumor effects in preclinical prostate cancer.

H. T. Sjoberg, Y. J. Philippou, A. L. Magnussen, I. D. Tullis, E. Bridges, A. Chatrian, J. Loefebvre, K. H. Tam, E. A. Murphy, J. Rittscher, D. Preise, L. Agemy, T. Yechezkel, S. C. Smart, P. Kinchesh, , R. J. Bryant

This paper investigates combining fractionated radiotherapy with vascular-targeted photodynamic therapy to enhance tumor control in preclinical prostate cancer models.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology

Anti-androgens induce Rab11a-exosome secretion in prostate cancer by suppressing amino acid-sensitive PAT4-mTORC1 signalling

K. McCormick, P. Sanitt, S.-J. Fan, J. D. Mason, A. L. Harris, F. Hamdy, C. Verrill, R. J. Bryant, D. C. I. Goberdhan

This study shows anti-androgens increase Rab11a-exosome secretion in prostate cancer by inhibiting PAT4-mTORC1 signaling, contributing to drug resistance.

bioRxiv · Sep 18, 2020 · PreprintCancer Biology