Author

R. J. Fontana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. J. Zhang· 2 shared J. Z. Sexton· 2 shared S. R. Meyer· 2 shared A. L. Jolly· 1 shared C. J. Childs· 1 shared D. Ferrer-Torres· 1 shared J. Kim· 1 shared J. R. Spence· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. J. Zhang

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2 papers

Recent·Most cited

A High-Throughput Microphysiological Liver Chip System to Model Direct and Idiosyncratic Drug-Induced Liver Injury Using Human Liver Organoids

C. J. Zhang, S. R. Meyer, M. A. Garcia, M. C. Procario, S. Yoo, A. L. Jolly, S. Kim, J. Kim, K. Baek, R. D. Kersten, R. J. Fontana, J. Z. Sexton

This paper introduces a high-throughput microfluidic liver chip system using human liver organoids to model drug-induced liver injury with improved sensitivity and prolonged drug exposure capabilities.

bioRxiv · Dec 1, 2023 · PreprintPharmacology & Toxicology

A Human Liver Organoid Screening Platform for DILI Risk Prediction

C. J. Zhang, S. R. Meyer, M. J. O'Meara, S. Huang, M. M. Capeling, D. Ferrer-Torres, C. J. Childs, J. R. Spence, R. J. Fontana, J. Z. Sexton

This study evaluates human liver organoids for DILI risk prediction using high-throughput screening and a liver-on-chip system, showing enhanced predictive capacity and physiological relevance.

bioRxiv · Aug 26, 2021Pharmacology & Toxicology