Author

R. J. Mostowy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Clements· 1 shared B. Smug· 1 shared C. Chewapreecha· 1 shared C. Fraser· 1 shared E. P. C. Rocha· 1 shared F. Lassalle· 1 shared G. M. Duggan· 1 shared G. S. Tomlinson· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. Clements

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ongoing shuffling of protein fragments diversifies core viral functions linked to interactions with bacterial hosts

B. Smug, K. Szczepaniak, E. P. C. Rocha, S. Dunin-Horkawicz, R. J. Mostowy

The paper quantifies domain mosaicism in phage proteins to show how protein modularity contributes to functional diversity and diversification across bacterial hosts.

bioRxiv · Dec 27, 2022Evolutionary Biology

Diversity and evolution of surface polysaccharide synthesis loci in Enterobacteriales

K. E. Holt, F. Lassalle, K. L. Wyres, R. Wick, R. J. Mostowy

The paper investigates the diversity and evolution of surface polysaccharide synthesis loci in Enterobacteriales using comparative genomics across 27,334 genomes, revealing dynamics driven by horizontal gene transfer and selective preservation.

bioRxiv · Jan 28, 2020Evolutionary Biology

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

V. Torraca, M. Kaforou, J. Watson, G. M. Duggan, H. Guerrero-Gutierrez, S. Krokowski, M. Hollinshead, T. B. Clarke, R. J. Mostowy, G. S. Tomlinson, V. Sancho-Shimizu, A. Clements, S. Mostowy

This paper shows that Shigella sonnei's O-antigen mediates neutrophil tolerance and increases dysentery incidence in zebrafish, suggesting O-antigen as a therapeutic target.

PLOS Pathogens · Dec 12, 2019Peer-reviewedMicrobiology

Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae

S. J. Lehtinen, C. Chewapreecha, W. P. Hanage, M. J. Lipsitch, N. J. Croucher, S. D. Bentley, P. Turner, C. Fraser, R. J. Mostowy

The study examines antibiotic resistance frequencies in Streptococcus pneumoniae and finds that horizontal gene transfer rates are not the main factor influencing these frequencies.

bioRxiv · Jun 11, 2019Evolutionary Biology