Author

X. V. Guo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:flow cytometry· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

E.-a. D. Amir· 2 shared A. Califano· 1 shared A. Figueroa· 1 shared A. H. Rahman· 1 shared A. Rahman· 1 shared A. Sette· 1 shared A. Z. Obradovic· 1 shared B. H. Lee· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

E.-a. D. Amir

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-Cell RNAseq Analysis Reveals Robust Anti-PD-1-Mediated Increase of Immune Infiltrate in Metastatic Castration-Sensitive Prostate Cancer

J. E. Hawley, A. Z. Obradovic, M. C. Dallos, E. A. Lim, K. Runcie, C. R. Ager, J. M. McKiernan, C. B. Anderson, G. J. Decastro, J. L. Weintraub, R. K. Virk, I. Lowy, J. Hu, M. G. Chaimowitz, X. V. Guo, , C. G. Drake

The paper analyzes single-cell RNAseq data from metastatic castration-sensitive prostate cancer patients treated with anti-PD-1 immunotherapy, showing increased immune infiltrate and identifying therapy-resistant tumor subpopulations and druggable targets.

bioRxiv · May 6, 2022 · PreprintCancer Biology

Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike

L. Liu, P. Wang, M. S. Nair, J. Yu, M. Rapp, Q. Wang, Y. Luo, J. F.-W. Chan, V. Sahi, A. Figueroa, X. V. Guo, G. Cerutti, J. Bimela, J. Gorman, T. Zhou, , D. D. Ho

The paper isolates and characterizes 61 SARS-CoV-2-neutralizing monoclonal antibodies from infected patients, identifying potent antibodies targeting multiple epitopes on the spike protein.

Nature · Jul 22, 2020Peer-reviewedMicrobiology

Development of a Comprehensive Antibody Staining Database using a Standardized Analytics Pipeline

E.-a. D. Amir, B. Lee, P. Badoual, M. Gordon, X. V. Guo, M. Merad, A. H. Rahman

The paper develops a standardized workflow for mass cytometry data analysis and presents an antibody staining database with insights into immune cell markers and fixation effects.

bioRxiv · May 2, 2019Immunology

A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer

B. H. Lee, G. Kelly, S. Bradford, M. Davila, X. V. Guo, E.-a. D. Amir, E. M. Thrash, M. Solga, J. Lannigan, B. Sellers, J. Candia, J. Tsang, R. Montgomery, S. Tamaki, T. Sigdel, , A. Rahman

The paper describes a modified Helios mass cytometer protocol that improves data quality and reduces inter-instrument variability in multi-center studies.

bioRxiv · Apr 5, 2019Immunology