Author

R. Kalra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. A. Lal· 1 shared A. Mazumder· 1 shared A. P. Gupta· 1 shared A. Poddar· 1 shared B. Vashishta· 1 shared C. Hindmarch· 1 shared C. M. Martin· 1 shared C.-H. Chen· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. A. Lal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Multi-omic and Multi-Species Analysis of Right Ventricular Failure

J. B. Mendelson, J. D. Sternbach, M. J. Doyle, L. Mills, L. M. Hartweck, W. Tollison, J. P. Carney, M. T. Lahti, R. W. Bianco, R. Kalra, F. Kazmirczak, C. Hindmarch, S. L. Archer, K. W. Prins, C. M. Martin

This study compares molecular pathways of right ventricular failure across pigs, rats, and humans using transcriptomics and proteomics, finding species-specific differences in fatty acid oxidation and electron transport chain regulation.

bioRxiv · Feb 8, 2023 · PreprintBiochemistry

Cocculus hirsutus -derived phytopharmaceutical drug has potent anti-dengue activity

A. Poddar, R. Shukla, H. Beesetti, U. Arora, R. K. Rajpoot, R. K. Shanmugam, S. Palla, K. Nayyar, D. Singh, V. Singamaneni, P. Gupta, A. P. Gupta, S. Gairola, Y. S. Bedi, T. Jain, , N. Khanna

This paper identifies Cocculus hirsutus-derived AQCH as a potent anti-dengue drug with in vitro and in vivo efficacy, characterized by five chemical markers and formulated into tablets for further development.

bioRxiv · Sep 18, 2020 · PreprintMicrobiology

Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

N. B. Punturi, S. Seker, V. Devarakonda, R. Kalra, C.-H. Chen, A. Mazumder, S.-Q. Li, T. Primeau, M. J. Ellis, S. M. Kavuri, S. Haricharan

This study shows that loss of MLH1, a mismatch repair gene, activates HER2 in ER+/HER2- breast cancer, making these cells sensitive to HER2 inhibitors.

bioRxiv · Jun 8, 2020Cancer Biology