R. Kalscheuer

α-Aminooxyacetic acid derivatives acting as pro-drugs against Mycobacterium tuberculosis

This study identifies novel anti-TB pro-drugs based on α-aminooxyacetic acid that are effective against M. tuberculosis and show low cytotoxicity.

The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113

This study identifies callyaerins as antitubercular agents targeting the M. tuberculosis-specific protein Rv2113, showing efficacy against drug-resistant strains with minimal cytotoxicity.

The mycotoxin Beauvericin exhibits immunostimulatory effects on dendritic cells via activating the TLR4 signaling pathway

This study identifies Beauvericin as an activator of dendritic cells via the TLR4 signaling pathway, suggesting its potential as a vaccine adjuvant or cancer immunotherapy.

The household resistome - frequency of beta-lactamases, class 1 integron and antibiotic resistant bacteria in the domestic environment

This study investigates the presence of antibiotic resistance genes and bacteria in household environments, finding higher levels of resistance genes in shower drains and reduced resistance after laundering and dishwashing.

A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate

This study investigates a temperature-sensitive mutation in Mycobacterium smegmatis glgE, showing it reduces enzyme activity and stability, leading to α-maltose-1-phosphate accumulation.