Author

R. Kretsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Assay:multiome· 1

Frequent Co-Authors

C. Bernardin· 1 shared C. Lin· 1 shared D. J. Mermelstein· 1 shared E. A. Pham· 1 shared G. D. Pintilie· 1 shared G. Nelson· 1 shared I. N. Zheludev· 1 shared J. A. McCammon· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

C. Bernardin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome

K. Zhang, I. N. Zheludev, R. J. Hagey, M. T.-P. Wu, R. Haslecker, Y. J. Hou, R. Kretsch, G. D. Pintilie, R. Rangan, W. Kladwang, S. Li, E. A. Pham, C. Bernardin, R. S. Baric, T. P. Sheahan, , R. Das

The paper uses cryo-EM and ASO experiments to study the SARS-CoV-2 FSE structure and its potential as an antiviral target, finding a complex tertiary structure but challenges in effective inactivation.

bioRxiv · Jul 18, 2020Biochemistry

Fast and Flexible GPU Accelerated Binding Free Energy Calculations within the AMBER Molecular Dynamics Package

D. J. Mermelstein, C. Lin, G. Nelson, R. Kretsch, J. A. McCammon, R. C. Walker

The paper introduces a GPU-accelerated implementation of thermodynamic integration in AMBER for faster and more efficient alchemical free energy calculations.

bioRxiv · Jan 15, 2018Biophysics