Author

E. A. Pham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

J. S. Glenn· 2 shared R. Das· 2 shared R. J. Hagey· 2 shared W. Kladwang· 2 shared A. Xiong· 1 shared B. Fram· 1 shared C. Bernardin· 1 shared G. D. Pintilie· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

J. S. Glenn

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Identification and targeting of a pan-genotypic influenza A virus RNA structure that mediates packaging and disease.

R. J. Hagey, M. Elazar, S. Tian, E. A. Pham, W. Kladwang, L. Ben-Avi, K. Nguyen, A. Xiong, M. Rabinovich, S. Schaffert, T. Avisar, B. Fram, P. Liu, P. Khatri, J. K. Taubenberger, , J. S. Glenn

This paper identifies a conserved RNA structure in influenza A virus that mediates packaging and disease, showing that targeting it inhibits virus production and reduces disease severity.

bioRxiv · Aug 21, 2021 · PreprintMicrobiology

Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome

K. Zhang, I. N. Zheludev, R. J. Hagey, M. T.-P. Wu, R. Haslecker, Y. J. Hou, R. Kretsch, G. D. Pintilie, R. Rangan, W. Kladwang, S. Li, E. A. Pham, C. Bernardin, R. S. Baric, T. P. Sheahan, , R. Das

The paper uses cryo-EM and ASO experiments to study the SARS-CoV-2 FSE structure and its potential as an antiviral target, finding a complex tertiary structure but challenges in effective inactivation.

bioRxiv · Jul 18, 2020Biochemistry