Author

R. L. Davis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:non-human primate· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. O'Connell· 3 shared T. S. Johnston· 3 shared A. Baidya· 2 shared A. Cook· 2 shared A. Dodson· 2 shared A. P. Werner· 2 shared A. R. Henry· 2 shared C. Tucker· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

S. O'Connell

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Control of cell proliferation by memories of mitosis

F. Meitinger, R. L. Davis, M. B. Martinez, A. K. Shiau, K. Oegema, A. Desai

The paper shows that mitotic duration memories control cell proliferation through a p53-based pathway, halting proliferation after extended or successive mitoses.

bioRxiv · Nov 14, 2022Cancer Biology

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones

N. S. Lima, M. Musayev, T. S. Johnston, D. A. Wagner, A. R. Henry, L. Wang, E. S. Yang, Y. Zhang, K. Birungi, W. P. Black, S. O'Dell, S. D. Schmidt, D. Moon, C. G. Lorang, B. Zhao, , P. D. Kwong

The paper examines antibody responses to SARS-CoV-2 variants, finding convergent epitope specificities, V gene usage, and public B cell clones across different variants.

bioRxiv · Mar 28, 2022Immunology

Computational study of the furin cleavage domain of SARS-CoV-2: delta binds strongest of extant variants

M. Z. Jawaid, A. Baidya, S. Jakovcevic, J. Lusk, R. Mahboubi-Ardakani, N. Solomon, G. Gonzalez, J. Arsuaga, M. Vazquez, R. L. Davis, D. L. Cox

The paper uses AlphaFold to predict furin cleavage domain structures and finds delta variant has strong binding, with some rare sequences matching it statistically.

bioRxiv · Jan 4, 2022 · PreprintBiophysics

Simulation of the omicron variant of SARS-CoV-2 shows broad antibody escape, weakened ACE2 binding, and modest increase in furin binding

M.- Z. Jawaid, A. Baidya, R. Mahboubi-Ardakani, R. L. Davis, D. L. Cox

The paper simulates the omicron variant's spike protein interactions with ACE2, antibodies, and furin to assess binding changes and potential disease impact.

bioRxiv · Dec 14, 2021 · PreprintBiophysics

Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

K. S. Corbett, M. Gagne, D. Wagner, S. O'Connell, S. R. Narpala, D. R. Flebbe, S. F. Andrew, R. L. Davis, B. Flynn, T. S. Johnston, C. Stringham, L. Lai, D. Valentin, A. Van Ry, Z. Flinchbaugh, , A Pekosz

mRNA-1273 boosted nonhuman primates show increased neutralizing antibody responses and protection against SARS-CoV-2 beta variant infection.

bioRxiv · Aug 11, 2021 · PreprintImmunology

Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

J. R. Francica, B. J. Flynn, K. E. Foulds, A. T. Noe, A. P. Werner, I. N. Morre, M. Gagne, T. S. Johnston, C. Tucker, R. L. Davis, B. Flach, S. O'Connell, S. F. Andrew, E. Lamb, D. R. Flebbe, , McDermott

This study shows that an AS03-adjuvanted SARS-CoV-2 spike protein vaccine induces strong antibody responses and protects nonhuman primates from viral challenge.

bioRxiv · Mar 2, 2021 · PreprintImmunology