Author

R. Lanotte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. Fouillen· 1 shared A. Kanso· 1 shared A. Musnier· 1 shared A. Pelegrin· 1 shared B. Mouillac· 1 shared C. Larbouret· 1 shared C. Mendre· 1 shared D. Bonnet· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Fouillen

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Author profile →

2 papers

Recent·Most cited

Biased activation of the vasopressin V2 receptor probed by NMR, paramagnetic ligands, and molecular dynamics simulations

G. Gaibelet, A. Fouillen, R. Stephanie, H. Orcel, C. Mendre, A. Kanso, R. Lanotte, J. Nguyen, J. Dimon, S. Urbach, R. Sounier, S. Granier, D. Bonnet, X. Cong, B. Mouillac, H. Demene

The paper uses NMR, molecular dynamics, and pharmacology to study conformational changes in the V2R receptor bound to different ligands, revealing a mechanism for Gs-biased agonism involving TM7 and TM3 interactions.

bioRxiv · Jun 6, 2023 · PreprintBiophysics

Biasing HER4 Tyrosine Kinase Signaling with Antibodies: Induction of Cell Death by Antibody-Dependent HER4 Intracellular Domain Trafficking

R. Lanotte, V. Garambois, N. Gaborit, C. Larbouret, A. Musnier, P. Martineau, A. Pelegrin, T. Chardes

This paper shows that anti-HER4 antibodies can mimic NRG1's tumor suppressor effects by inducing 4ICD mitochondrial trafficking and cell death in cancer cells.

bioRxiv · Dec 20, 2019Cancer Biology