R. Lipowsky

Lipid packing and cholesterol content regulate membrane wetting and remodeling by biomolecular condensates.

This study shows that lipid packing and cholesterol content influence condensate-membrane interactions, with increased packing reducing condensate affinity.

Photoswitchable endocytosis of biomolecular condensates in giant vesicles

This study shows light-controlled endocytosis of biomolecular condensates in giant vesicles using photoswitchable lipids, demonstrating reversible and tunable membrane-condensate interactions.

Wetting and complex remodeling of membranes by biomolecular condensates

This study investigates how protein condensates interact with membranes, leading to morphological changes and introduces a theoretical framework to describe these interactions.

Stepwise remodelling and subcompartment formation in individual vesicles by three ESCRT-III proteins

This study uses single-vesicle experiments to show how three ESCRT-III proteins reshape membranes by modulating stiffness and curvature, forming intraluminal vesicles without ATP.

Binding of His-tagged fluorophores to lipid bilayers and giant vesicles

The paper studies the binding of His-tagged fluorophores to lipid bilayers and giant vesicles, finding that 6H-FITC is quenched by anchor lipids and has a lower dissociation constant than 6H-GFP.

Super-resolution imaging of highly curved membrane structures in giant vesicles encapsulating molecular condensates

This study uses super-resolution microscopy to image highly curved membrane structures in synthetic cells, revealing membrane properties and their agreement with theoretical predictions.

Structural variability and concerted motions of the T cell receptor - CD3 complex

This study uses molecular dynamics simulations to analyze structural variability and motions of the TCR-CD3 complex, revealing tilt angles and coupled domain movements.

Super-elasticity of plasma- and synthetic membranes by coupling of membrane asymmetry and liquid-liquid phase separation

The paper demonstrates that preserving plasma membrane structure and composition during isolation enables vesicles with cell-like elasticity, achieved through membrane asymmetry and liquid-liquid phase separation.