T. Robinson

The Discovery of Small Molecule Inhibitors of cFLIP that Sensitise Tumour Cells to TRAIL

This paper identifies small molecule inhibitors of cFLIP that enhance TRAIL-induced apoptosis in breast cancer cells and improves their potency through structure-activity relationship studies.

Escape problem of magnetotactic bacteria - physiological magnetic field strengths help magnetotactic bacteria navigate in simulated sediments

This study shows that magnetotactic bacteria achieve optimal swimming throughput in environments mimicking natural sediments at physiological magnetic field strengths.

Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer

This study shows that hematopoietic Dnmt3a haploinsufficiency worsens colitis-associated colon cancer by promoting angiogenesis, which can be targeted with axitinib.

Stepwise remodelling and subcompartment formation in individual vesicles by three ESCRT-III proteins

This study uses single-vesicle experiments to show how three ESCRT-III proteins reshape membranes by modulating stiffness and curvature, forming intraluminal vesicles without ATP.

Controlled adhesion, membrane pinning and vesicle transport by Janus particles

This study uses Janus particles to control adhesion and transport in artificial cell membranes through electrostatic and magnetic interactions.

Super-resolution imaging of highly curved membrane structures in giant vesicles encapsulating molecular condensates

This study uses super-resolution microscopy to image highly curved membrane structures in synthetic cells, revealing membrane properties and their agreement with theoretical predictions.

Single-cell motion of magnetotactic bacteria in microfluidic confinement: interplay between surface interaction and magnetic torque

This study tracks magnetotactic bacteria in microfluidic chambers under magnetic fields, showing trajectory diversity due to wall interactions and magnetic torque, and highlights cell-to-cell heterogeneity.