D. Milovanovic

Condensates of synaptic vesicles and synapsin are molecular beacons for actin sequestering and polymerization

The paper investigates how synapsin-SV condensates organize presynaptic actin through LLPS, revealing their role in SV clustering and actin polymerization in lamprey and mammalian synapses.

Lipid packing and cholesterol content regulate membrane wetting and remodeling by biomolecular condensates.

This study shows that lipid packing and cholesterol content influence condensate-membrane interactions, with increased packing reducing condensate affinity.

Protein thiol alterations drive aberrant phase separation in aging

This study shows that aging-related changes in cysteine posttranslational modifications alter protein phase separation, leading to aggregation and neurodegeneration.

A nano-liquid hub integrating growth and immune-evasion signaling to promote cell survival

The paper identifies GEM, a nano-liquid hub that integrates growth and immune-evasion signaling to enhance cell survival in mice.

Physics-based inverse design of cholesterolattracting transmembrane helices reveals aparadoxical role of hydrophobic length

This paper uses evolutionary algorithms and molecular dynamics to identify optimal cholesterol-attracting transmembrane helices, revealing a paradoxical role of hydrophobic length.

More than just oil droplets in water: surface tension and viscosity of protein condensates quantified by micropipette aspiration

This paper develops a micropipette-based technique to quantify surface tension and viscosity of biomolecular condensates without labeling or surface wetting effects, demonstrating its accuracy with LAF-1 RGG domains and ATPS.

SARS-CoV-2 infection induces mixed M1/M2 phenotype in circulating monocytes and alterations in both dendritic cell and monocyte subsets

The paper examines how SARS-CoV-2 infection affects monocyte and dendritic cell subsets in mild and severe cases, finding mixed M1/M2 phenotypes and immune cell depletion in severe cases.

Cell surface mechanics gate stem cell differentiation

This study shows that changes in cell surface mechanics control stem cell differentiation by regulating membrane-to-cortex attachment in mouse embryonic stem cells.