R. Matsumoto

Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

The paper profiles immune cell RNA and protein expression across tissues and age to identify tissue-specific and age-related immune signatures.

A high-fidelity in vitro model of the human intestinal epithelium

This paper develops an in vitro model of the human intestinal epithelium that closely mimics in vivo cell types using single-cell transcriptomics and a biomedical foundation model.

Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotypic organization

This study sequenced elasmobranch genomes to reveal evolutionary trends in vertebrate karyotypic organization, identifying a shark X chromosome and patterns of intragenomic heterogeneity.

Lung evolution in vertebrates and the water-to-land transition

This study investigates lung morphology in living lunged osteichthyans to determine the ancestral state of vertebrate lungs as unpaired, evolving to paired lungs in tetrapod lineages.

Genome analyses reveal the hybrid origin of the staple food crop white Guinea yam

This study reveals the hybrid origin of white Guinea yam through genomic analysis, showing it arose from crosses between D. praehensilis and D. abyssinica with significant introgression around the SWEETIE gene.