Author

L. B. Jarvis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Assay:proteomics· 2

Frequent Co-Authors

J. L. Jones· 4 shared K. Saeb-Parsy· 4 shared D. Rainbow· 3 shared O. Suchanek· 3 shared C. Xu· 2 shared E. Needham· 2 shared K. Polanski· 2 shared K. T. Mahbubani· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersImmunology

J. L. Jones

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4 papers

Recent·Most cited

Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

S. B. Wells, D. Rainbow, M. Mark, P. P. A. S. Szabo, C. Ergen, A. R. Maceiras, D. P. Caron, E. Rahmani, E. Benuck, V. V. P. Amiri, D. Chen, A. Wagner, S. K. Howlett, L. B. Jarvis, K. L. Elli, , N. Yosef

The paper profiles immune cell RNA and protein expression across tissues and age to identify tissue-specific and age-related immune signatures.

Nature Immunology · Aug 13, 2025Peer-reviewedImmunology

Hiding in Plain Sight: Thymic CD8+FOXP3+Tregs sequester CD25 and are enriched in human tissues

L. B. Jarvis, S. K. Howlett, D. Rainbow, V. Coppard, R. Ferreira, E. Needham, A. Prabhu, S. Alkwai, L. Ellis, Z. Georgieva, O. Suchanek, H. S. Mousa, K. T. Mahbubani, K. Saeb-Parsy, L. S. Wicker, J. L. Jones

The paper identifies CD8+FOXP3+ Tregs enriched in human tissues, expressing intracellular CD25 and tissue residency markers, and demonstrates their therapeutic potential and association with disease states.

bioRxiv · Dec 24, 2023 · PreprintImmunology

Cross-tissue immune cell analysis reveals tissue-specific adaptations and clonal architecture across the human body

C. Dominguez Conde, T. Gomes, L. B. Jarvis, C. Xu, S. Howlett, D. Rainbow, O. Suchanek, H. King, L. Mamanova, K. Polanski, N. Huang, E. Fasouli, K. Mahbubani, M. Prete, E. Tuck, , S. A. Teichmann

The paper analyzes immune cell diversity across 15 human tissues using single-cell RNA sequencing and VDJ sequencing, revealing tissue-specific features and clonal architecture of T and B cells.

bioRxiv · Apr 28, 2021Immunology

Distinct microbial and immune niches of the human colon

K. R. James, T. Gomes, R. Elmentaite, N. Kumar, E. L. Gulliver, H. W. King, M. D. Stares, B. R. Bareham, J. R. Ferdinand, V. Petrova, K. Polanski, S. C. Forster, L. B. Jarvis, O. Suchanek, S. Howlett, , S. A. Teichmann

The paper examines microbial and immune cell interactions in the human colon, identifying distinct immune niches and T cell profiles along the colon.

bioRxiv · Dec 12, 2019Immunology