M. Hoshino

Meis1 isoform diversity orchestrates neural progenitor differentiation by regulating ATOH1 degradation at distinct subcellular compartments

The paper identifies functionally antagonistic Meis1 isoforms that regulate ATOH1 degradation through distinct subcellular localization and E3 ligase interactions, affecting neural progenitor differentiation.

Origin and evolutionary trajectories of brown algal sex chromosomes

The paper analyzes brown algal genomes to trace the origin and evolution of U/V sex chromosomes, revealing gene gain-driven evolution and the demise of these systems through hermaphroditism and gene hierarchy shifts.

PARALLEL LOSS OF SEX IN FIELD POPULATIONS OF A BROWN ALGA SHEDS LIGHT ON THE MECHANISMS UNDERLYING THE EMERGENCE OF ASEXUALITY

The paper investigates the molecular mechanisms of asexual reproduction emergence in brown algae, finding convergent gene expression changes and a key autosomal locus associated with the loss of sex.

Three-dimensional visualization of moss rhizoid system by refraction-contrast X-ray micro-computed tomography

This study visualizes and quantitatively analyzes the 3D rhizoid system of moss using X-ray micro-CT and machine learning, revealing its dense structure similar to vascular plant roots.

Lung evolution in vertebrates and the water-to-land transition

This study investigates lung morphology in living lunged osteichthyans to determine the ancestral state of vertebrate lungs as unpaired, evolving to paired lungs in tetrapod lineages.

Binding mechanism underlying FIH-1 suppression caused by the N-terminal disordered region of Mint3

This study investigates the binding mechanism between Mint3 and FIH-1, identifying a novel core site and thermodynamic contributions of Mint3's disordered region.

Visualization of Arabidopsis root system architecture in 3D by refraction-contrast X-ray micro-computed tomography

The paper uses refraction-contrast X-ray micro-CT to visualize Arabidopsis root system architecture in 3D, distinguishing roots from rockwool fibers in microgravity conditions.