Author

R. Modhurima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

L. I. Zon· 2 shared A. Dedeilia· 1 shared A. M. Cox· 1 shared A. McConnell· 1 shared A. Thomas· 1 shared B. J. Abraham· 1 shared C. G. Ludwig· 1 shared C. K. Kaufman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

L. I. Zon

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Specific oncogene activation of the cell of origin in mucosal melanoma

S. Babu, J. Chen, E. Robitschek, C. S. Baron, A. McConnell, C. Wu, A. Dedeilia, M. Sade-Feldman, R. Modhurima, M. P. Manos, K. Y. Chen, A. M. Cox, C. G. Ludwig, J. Yang, M. Kellis, , M. L. Insco

This study develops a zebrafish model of mucosal melanoma by activating an oncogene and inactivating tumor suppressors, revealing that internal melanocytes give rise to tumors with distinct transcriptional and chromatin features.

bioRxiv · Apr 22, 2024Cancer Biology

SATB2 induction of a neural crest mesenchyme-like program drives invasion and drug resistance in melanoma

M. Fazio, E. van Rooijen, M. Dang, G. van de Hoek, J. Ablain, J. K. Mito, S. Yang, A. Thomas, J. Michael, T. Fabo, R. Modhurima, P. Pessina, C. K. Kaufman, Y. Zhou, R. M. White, L. I. Zon

This study shows SATB2 drives melanoma invasion and drug resistance by inducing a neural crest mesenchyme-like transcriptional program in zebrafish and human models.

bioRxiv · Nov 1, 2020Cancer Biology