LRH-1 Mitigates Intestinal Inflammatory Disease by Maintaining Epithelial Homeostasis and Cell Survival
J. R. Bayrer, H. Wang, R. Nattiv, M. Suzawa, H. S. Escusa, R. J. Fletterick, O. D. Klein, D. D. Moore, H. A. Ingraham
This study shows that LRH-1 maintains intestinal epithelial homeostasis and cell survival, and its overexpression mitigates inflammatory damage in IBD models.
bioRxiv · May 22, 2018Cell Biology