Author

J. Gibson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Bojarczuk· 1 shared A. K. Lagendijk· 1 shared A. Kamuyango· 1 shared A. Kelsey· 1 shared A. Samadi· 1 shared A. Z. Fire· 1 shared B. M. Hogan· 1 shared B. Wang· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperPathology

A. Bojarczuk

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A genetic and microscopy toolkit for live imaging of whole-body regeneration in Macrostomum lignano

R. N. Hall, H. Li, C. Chai, S. Vermeulen, R. Rio, E. S. Song, J. Gibson, M. Prakash, A. Z. Fire, B. Wang

This paper develops a toolkit for live imaging of whole-body regeneration in flatworms, revealing neuron regenerative limitations and independent nerve cord reconnection.

bioRxiv · Apr 28, 2024 · PreprintBioengineering

Immune experience at time of circulation and time since virus circulation are predictors of HAI titre

J. Gibson, C. Russell, S. P. de Jong

The paper uses statistical models to show that immune experience and time since virus circulation predict haemagglutination inhibition titres in individuals.

bioRxiv · Jul 25, 2023 · PreprintImmunology

Combination EZH2 inhibition and retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

E. OBrien, C. Tse, I. Tracy, I. Reddin, J. Selfe, J. Gibson, W. Tapper, R. J. Pengelly, J. Gao, E. Aladowicz, G. Petts, K. Thway, S. Popov, A. Kelsey, T. J. Underwood, , Z. S. Walters

This study shows that combining EZH2 inhibition with retinoic acid treatment reduces RMS cell proliferation by inducing apoptosis or differentiation depending on the RMS subtype.

bioRxiv · Jun 12, 2023 · PreprintCancer Biology

Extracellular ATP drives pancreatic cancer cell invasion via purinergic receptor-integrin interactions

E. Tomas Bort, M. Joseph, Q. Wang, E. Carter, N. Roth, J. Gibson, A. Samadi, H. Kocher, S. Simoncelli, P. J. McCormick, R. P. Grose

This study identifies P2RY2 as a key purinergic receptor involved in pancreatic cancer invasion through interactions with integrins, suggesting therapeutic targeting potential.

bioRxiv · Oct 24, 2022Cancer Biology

PD-L1 blockade restores CAR T cell activity through IFNγ-regulation of CD163+ macrophages

Y. Yamaguchi, J. Gibson, K. Ou, R. H. Ng, V. D. Jonsson, J. C. Zarif, P. P. Lee, X. Wang, C. Martinez, T. B. Dorff, S. J. Forman, S. J. Priceman

This study shows that PD-L1 blockade enhances CAR T cell activity by altering macrophage phenotypes through IFNγ signaling in the tumor microenvironment.

bioRxiv · Jan 25, 2022 · PreprintImmunology

Blood vessel occlusion by Cryptococcus neoformans is a mechanism for hemorrhagic dissemination of infection

J. Gibson, A. Bojarczuk, R. J. Evans, A. Kamuyango, R. Hotham, A. K. Lagendijk, B. M. Hogan, P. W. Ingham, S. Renshaw, S. Johnston

The paper investigates how Cryptococcus neoformans causes vessel damage and dissemination in zebrafish, finding that vascular growth and stiffness increase dissemination events.

bioRxiv · Mar 17, 2020 · PreprintPathology