Caloric Restriction recovers impaired β-cell-β-cell coupling, calcium oscillation coordination and insulin secretion in prediabetic mice
M. E. C. do Amaral, V. Kravets, J. M. Dwulet, N. L. Farnsworth, R. Piscopio, W. E. Schleicher, J. G. Miranda, R. K. Benninger
This study shows caloric restriction improves β-cell coupling, calcium oscillations, and insulin secretion in prediabetic mice by restoring Cx36 gap junction function.
bioRxiv · Mar 3, 2020Physiology