Author

N. L. Farnsworth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

R. K. Benninger· 3 shared J. G. Miranda· 2 shared J. M. Dwulet· 2 shared V. Kravets· 2 shared W. E. Schleicher· 2 shared A. Heintz· 1 shared C. G. Johansen· 1 shared C. H. Levitt· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

R. K. Benninger

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Author profile →

3 papers

Recent·Most cited

Cleavage of protein kinase c δ by caspase-3 mediates pro-inflammatory cytokine-induced apoptosis in pancreatic islets

J. Collins, R. A. Piscopio, M. E. Reyland, C. G. Johansen, R. K. Benninger, N. L. Farnsworth

This study identifies PKCδ's role in cytokine-induced apoptosis in pancreatic β-cells, showing that caspase-3 cleavage and nuclear translocation of PKCδ are required for cytokine-mediated β-cell death.

Journal of Biological Chemistry · Sep 1, 2024Peer-reviewedCell Biology

RESTORING CONNEXIN-36 FUNCTION IN DIABETOGENIC ENVIRONMENTS PRECLUDES MOUSE AND HUMAN ISLET DYSFUNCTION

J. R. St Clair, M. J. Westacott, J. G. Miranda, N. L. Farnsworth, V. Kravets, W. E. Schleicher, J. M. Dwulet, C. H. Levitt, A. Heintz, N. W. F. Ludin, R. K. Benninger

This study shows that restoring Cx36 gap junction function in diabetic conditions improves islet function in both mice and humans.

bioRxiv · Nov 3, 2020Biophysics

Caloric Restriction recovers impaired β-cell-β-cell coupling, calcium oscillation coordination and insulin secretion in prediabetic mice

M. E. C. do Amaral, V. Kravets, J. M. Dwulet, N. L. Farnsworth, R. Piscopio, W. E. Schleicher, J. G. Miranda, R. K. Benninger

This study shows caloric restriction improves β-cell coupling, calcium oscillations, and insulin secretion in prediabetic mice by restoring Cx36 gap junction function.

bioRxiv · Mar 3, 2020Physiology