Author

G. A. Knappe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

E.-C. Wamhoff· 2 shared M. Bathe· 2 shared A. A. Burds· 1 shared A. B. Balazs· 1 shared A. K. Barczak· 1 shared A. Romanov· 1 shared A. Schmidt· 1 shared B. M. Hauser· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

E.-C. Wamhoff

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice

E.-C. Wamhoff, G. A. Knappe, A. A. Burds, R. R. Du, B. Neun, S. Difilippantonio, C. Sanders, E. Edmondson, J. L. Matta, M. Dobrovolskaia, M. Bathe

This study evaluates the acute toxicity and biodistribution of non-modified wireframe DNA origami nanoparticles in mice, finding no toxicity and minimal immunotoxicity.

bioRxiv · Feb 25, 2023 · PreprintPharmacology & Toxicology

Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

E.-C. Wamhoff, L. Ronsard, J. Feldman, G. A. Knappe, B. M. Hauser, A. Romanov, E. Lam, K. St. Denis, J. Boucau, A. K. Barczak, A. B. Balazs, A. Schmidt, D. Lingwood, M. Bathe

This study shows DNA origami scaffolds enhance antibody responses to SARS-CoV-2 RBD without inducing immune memory against the scaffold itself, compared to protein-based VLPs.

bioRxiv · Aug 16, 2022Immunology