Author

T. R. Shepherd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:DNA methylation· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Bathe· 5 shared H. Huang· 2 shared R. Veneziano· 2 shared S. Ratanalert· 2 shared C. M. Ackerman· 1 shared C. Tao· 1 shared D. J. Irvine· 1 shared E.-C. Wamhoff· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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5 shared papersBioengineering

M. Bathe

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

3D RNA-scaffolded wireframe origami

M. F. Parsons, M. F. Allan, S. Li, T. R. Shepherd, S. Ratanalert, K. Zhang, K. M. Pullen, W. Chiu, S. Rouskin, M. Bathe

This paper designs, fabricates, and characterizes 3D RNA-scaffolded wireframe origami structures using different RNA sequences, revealing structural insights and demonstrating the potential for functional RNA scaffolds.

bioRxiv · Aug 15, 2022Bioengineering

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

R. Veneziano, T. Moyer, M. B. Stone, T. R. Shepherd, W. R. Schief, D. J. Irvine, M. Bathe

This study uses DNA origami to investigate how antigen organization affects B-cell activation, finding that optimal spacing and valency enhance signaling.

bioRxiv · Feb 16, 2020Immunology

Random access DNA memory in a scalable, archival file storage system

J. L. Banal, T. R. Shepherd, J. D. Berleant, H. Huang, M. Reyes, C. M. Ackerman, P. Blainey, M. Bathe

This paper demonstrates a method to enable random access of DNA-encoded files in large-scale archival storage by using silica capsules with barcode labels for efficient file selection.

bioRxiv · Feb 5, 2020Bioengineering

Bioproduction of single-stranded DNA from isogenic miniphage

T. R. Shepherd, R. R. Du, H. Huang, E.-C. Wamhoff, M. Bathe

This paper demonstrates the scalable production of custom-length single-stranded DNA (cssDNA) using engineered miniphage in E. coli, enabling applications in DNA origami and archival data storage.

bioRxiv · Jan 16, 2019 · PreprintBioengineering

Enzymatic synthesis of gene-length single-stranded DNA

R. Veneziano, T. R. Shepherd, S. Ratanalert, L. Bellou, C. Tao, M. Bathe

This paper develops an enzymatic method to synthesize long ssDNA sequences (>15 kb) with controlled nucleotide composition for therapeutic and imaging uses.

bioRxiv · Oct 10, 2017Bioengineering