Author

R. R. Lobb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. J. Hackel· 2 shared C. Ambrose· 2 shared L. Su· 2 shared L. Wu· 2 shared P. D. Rennert· 2 shared A. A. Hombach· 1 shared A. Birt· 1 shared A. Harthorn· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

B. J. Hackel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CAR-T Engager Proteins Optimize Anti-CD19 CAR-T Cell Therapies for Lymphoma

L. Su, L. Wu, R. R. Lobb, P. D. Rennert, C. Ambrose

This paper introduces a CAR-T Engager protein that prevents and reverses lymphoma relapse by maintaining CD19 antigen presence on cancer cells.

bioRxiv · May 30, 2022Cancer Biology

Engineered protein-small molecule conjugates empower selective enzyme inhibition

A. K. Lewis, A. Harthorn, S. M. Johnson, R. R. Lobb, B. J. Hackel

The paper introduces a platform to create protein-small molecule hybrids (PriSMs) that enhance enzyme inhibition specificity and potency compared to small molecules or proteins alone.

bioRxiv · May 5, 2021Bioengineering

CD19-targeting CAR T cells potently redirected to kill solid tumor cells

C. Ambrose, L. Su, L. Wu, F. J. Dufort, T. Stanford, A. Birt, B. J. Hackel, A. A. Hombach, H. Abken, R. R. Lobb, P. D. Rennert

This paper develops CD19-targeting CAR T cells that secrete bridging proteins to enhance tumor targeting and cytotoxicity in solid tumors.

bioRxiv · Mar 25, 2020Cancer Biology