Author

R. S. LaRue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. A. Farrar· 4 shared T. P. Knutson· 3 shared L. M. Heltemes-Harris· 2 shared S. A. Munro· 2 shared A. L. Sarver· 1 shared B. McClusky· 1 shared C. H. O'Connor· 1 shared C. M. Henzler· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersImmunology

M. A. Farrar

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4 papers

Recent·Most cited

Nuclear corepressors NCOR1 and NCOR2 entrain thymocytesignaling, selection, and emigration

N. A. David, R. D. Lee, R. S. LaRue, R. LaRue, M. A. Farrar

This study shows NCOR1 and NCOR2 regulate thymocyte signaling, selection, and emigration, with combined deletion causing developmental blocks and altered signaling pathways.

bioRxiv · Sep 27, 2023 · PreprintImmunology

Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cells

L. E. Sjaastad, D. L. Owen, S. Joo, T. P. Knutson, C. H. O'Connor, B. McClusky, R. S. LaRue, R. A. Langlois, M. A. Farrar

This study identifies two distinct regulatory T cell subsets in the lung during influenza infection and shows their role in modulating IgA+ B cells, with similar patterns observed in COVID-19 patients.

bioRxiv · Sep 19, 2022 · PreprintImmunology

Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia

L. M. Heltemes-Harris, G. Hubbard, R. S. LaRue, S. A. Munro, T. P. Knutson, R. Yang, C. M. Henzler, T. K. Starr, A. L. Sarver, s. M. Kornblau, M. A. Farrar

This study identifies cooperating mutations that drive leukemia in mice with B cell transcription factor defects and suggests PDK1 inhibitors as potential therapies.

bioRxiv · Nov 25, 2020Cancer Biology

Single-cell analysis of developing B cells reveals dynamic gene expression networks that govern B cell development and transformation

R. Lee, S. A. Munro, T. P. Knutson, R. S. LaRue, L. M. Heltemes-Harris, M. A. Farrar

The paper uses single-cell transcriptomics and proteomics to study B cell development, identifying novel proliferative phases and dynamic gene expression patterns linked to B cell transformation.

bioRxiv · Jun 30, 2020 · PreprintImmunology