Author

T. K. Starr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. C. Nelson· 1 shared A. Chauhan· 1 shared A. Khoruts· 1 shared A. L. Sarver· 1 shared B. R. Webber· 1 shared B. S. Moriarity· 1 shared B. Walcheck· 1 shared C. J. Yuan· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. C. Nelson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Fecal Microbiota Restoration Modulates the Microbiome in Inflammation-Driven Colorectal Cancer

T. J. Gates, C. J. Yuan, M. Shetty, T. Kaiser, A. C. Nelson, A. Chauhan, T. K. Starr, C. Staley, S. Subramanian

The paper examines microbiome changes in inflammation-driven colorectal cancer using a mouse model, finding increased Akkermansia in microbiome-restored mice and elevated lipocalin-2 in unrestored animals.

bioRxiv · Dec 28, 2022Microbiology

Dissecting the Cellular Landscape and Transcriptome Network in Viral Myocarditis by Single-Cell RNA Sequencing

N. Lasrado, N. Borcherding, R. Arumugam, T. K. Starr, J. Reddy

This study uses single-cell RNA sequencing to analyze heart cells from healthy and myocarditic mice, identifying changes in immune and non-immune cell populations and their transcriptomic roles in viral myocarditis.

bioRxiv · May 16, 2021Immunology

Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia

L. M. Heltemes-Harris, G. Hubbard, R. S. LaRue, S. A. Munro, T. P. Knutson, R. Yang, C. M. Henzler, T. K. Starr, A. L. Sarver, s. M. Kornblau, M. A. Farrar

This study identifies cooperating mutations that drive leukemia in mice with B cell transcription factor defects and suggests PDK1 inhibitors as potential therapies.

bioRxiv · Nov 25, 2020Cancer Biology

A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy

E. J. Pomeroy, J. T. Hunzeker, M. T. Kluesner, M. R. Crosby, W. S. Lahr, L. Bendzick, J. S. Miller, B. R. Webber, M. A. Geller, B. Walcheck, M. Felices, T. K. Starr, B. S. Moriarity

This paper develops a CRISPR/Cas9-based method to edit human NK cells, enhancing their anti-cancer activity by knocking out ADAM17 and PD1.

bioRxiv · Sep 29, 2018Immunology

Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

M. B. Burns, E. Montassier, J. Abrahante, S. Priya, D. E. Niccum, A. Khoruts, T. K. Starr, D. Knights, R. Blekhman

This study identifies correlations between colorectal cancer mutations and microbial communities in the tumor microenvironment, suggesting potential functional interactions and implications for diagnostics and therapies.

bioRxiv · Mar 13, 2018Cancer Biology