Author

R. Straver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. de Ridder· 3 shared A. Marcozzi· 1 shared A. Merenda· 1 shared A. R. Keijzer· 1 shared B. J. P. Huntly· 1 shared B. Peltenburg· 1 shared C. Jamieson· 1 shared C. Terhaard· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

J. de Ridder

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Author profile →

3 papers

Recent·Most cited

Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model

N. Sakakini, R. Straver, D. Azazi, S. J. Horton, R. Asby, S. E. Richardson, P. Madrigal, E. E. Soilleux, R. J. M. Bashford-Rogers, J. de Ridder, B. J. P. Huntly

bioRxiv · Mar 25, 2024 · PreprintCancer Biology

Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway

S. F. Plugge, H. Ma, J. Y. van der Vaart, J. Sprangers, F. H. M. Morsink, D. Xanthakis, C. Jamieson, K. B. W. Stroot, A. R. Keijzer, T. Margaritis, T. Candelli, R. Straver, J. de Ridder, F. C. P. Holstege, W. W. J. de Leng, , M. M. Maurice

This study shows that LKB1 loss in intestinal cells leads to a pre-malignant state linked to serrated colorectal cancer, which is amplified by loss-of-heterozygosity.

bioRxiv · Jul 17, 2023 · PreprintCancer Biology

Accurate detection of circulating tumor DNA using nanopore consensus sequencing

A. Marcozzi, M. Jager, M. Elferink, R. Straver, J. H. van Ginkel, B. Peltenburg, L.-T. Chen, I. Renkens, J. van Kuik, C. Terhaard, R. de Bree, L. A. Devriese, S. M. Willems, W. P. Kloosterman, J. de Ridder

This paper introduces CyclomicsSeq, a nanopore sequencing method that improves ctDNA detection sensitivity, enabling accurate TP53 mutation detection at 0.02% frequency in head-and-neck cancer patients.

bioRxiv · Jul 14, 2020Cancer Biology