A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8
K. V. Tarasov, K. Chakir, D. R. Riordon…·E. G. Lakatta
This study shows that cardiac-specific overexpression of AC8 in mice leads to adaptive cardiac changes resembling cancer-like survival mechanisms without heart failure.