Author

C. H. Morrell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Assay:electrophysiology· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

E. G. Lakatta· 4 shared A. E. Lyashkov· 2 shared D. Yang· 2 shared I. Ahmet· 2 shared J. Zhang· 2 shared M. Wang· 2 shared R. deCabo· 2 shared R. Telljohann· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersPhysiology

E. G. Lakatta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8

K. V. Tarasov, K. Chakir, D. R. Riordon, A. E. Lyashkov, I. Ahmet, M. G. Perino, A. J. Silvester, J. Zhang, M. Wang, Y. O. Lukyanenko, J.-H. Qu, M. C.-R. Barrera, M. Juhaszova, Y. S. Tarasova, B. Ziman, , E. G. Lakatta

This study shows that cardiac-specific overexpression of AC8 in mice leads to adaptive cardiac changes resembling cancer-like survival mechanisms without heart failure.

bioRxiv · May 20, 2022Physiology

Emergence of Heartbeat Frailty in Advanced Age: Perspectives from Life-Long EKG Recordings in Mice

J. M. Moen, C. H. Morrell, I. Ahmet, M. G. Matt, M. Davoodi, M. Petr, S. Charles, R. deCabo, Y. Yaniv, E. G. Lakatta

This study tracks EKG recordings in mice to identify age-related changes in heart rhythm variability, linking them to signs of cardiac and systemic frailty in advanced age.

bioRxiv · Jan 12, 2022 · PreprintPhysiology

The Inflammatory Role of Milk Fat Globule Epidermal Growth Factor VIII in Angiotensin II Induced Arterial Remodeling

L. Ni, L. Liu, W. Zhu, R. Telljohann, J. Zhang, R. E. Monticone, K. R. McCraw, C. Liu, C. H. Morrell, P. Garrido-Gil, J. L. Labandeira-Garcia, E. G. Lakatta, M. Wang

This study shows that MFG-E8 promotes Ang II-induced arterial inflammation and remodeling in aging, and its deficiency reduces these effects.

bioRxiv · Mar 11, 2021 · PreprintPathology

Ca2+ and Membrane Potential Transitions During Action Potentials are Self-Similar to Each Other and to Variability of AP Firing Intervals Across the Broad Physiologic Range of AP Intervals During Autonomic Receptor Stimulation

D. Yang, C. H. Morrell, A. E. Lyashkov, S. Tagirova, I. Zahanich, Y. Yaniv, T. M. Vinogradova, B. D. Ziman, V. A. Maltsev, E. G. Lakatta

The paper shows that Ca2+ and membrane potential transitions during action potentials in SAN cells are self-similar across species and autonomic stimulation, indicating long-range correlations in their kinetic behavior.

bioRxiv · Sep 1, 2020 · PreprintBiophysics