Author

K. Chakir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

I. Ahmet· 3 shared C. Morrell· 2 shared E. G. Lakatta· 2 shared M. G. Perino· 2 shared M. Ranek· 2 shared R. deCabo· 2 shared A. E. Lyashkov· 1 shared A. Gupta· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersPhysiology

I. Ahmet

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Age-associated failure of efficient cardiac proteostatic adaptations to chronic cAMP-stress is associated with accelerated heart aging

M. G. Perino, M. Calvo-Rubio Barrera, D. Riordon, G. Agnetti, K. Tarasov, A. Parveen, K. Chakir, C. Morrell, I. Ahmet, A. Lyashkov, Y. Lukyanenko, Y. Tarasova, J. Qu, H. Kadioglu, M. Ranek, , E. Lakatta

This study shows that aging impairs proteostatic mechanisms in mice with cardiac-specific over-expression of adenylyl cyclase VIII, leading to accelerated heart aging and cardiomyopathy.

bioRxiv · Aug 13, 2023 · PreprintCell Biology

The Therapeutic Effects of Long-term Photobiomodulation on Aging in Mice

I. Ahmet, S. B. Syed, K. Chakir, C. Morrell, P. Arany, E. G. Lakatta

This study shows that long-term photobiomodulation therapy improves healthspan and reduces age-related deterioration in mice.

bioRxiv · Aug 5, 2023 · PreprintPhysiology

A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8

K. V. Tarasov, K. Chakir, D. R. Riordon, A. E. Lyashkov, I. Ahmet, M. G. Perino, A. J. Silvester, J. Zhang, M. Wang, Y. O. Lukyanenko, J.-H. Qu, M. C.-R. Barrera, M. Juhaszova, Y. S. Tarasova, B. Ziman, , E. G. Lakatta

This study shows that cardiac-specific overexpression of AC8 in mice leads to adaptive cardiac changes resembling cancer-like survival mechanisms without heart failure.

bioRxiv · May 20, 2022Physiology