Author

R. Varadhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Fearnow· 1 shared A. Marple· 1 shared A. R. Moliterno· 1 shared A. Tam· 1 shared B. Paun· 1 shared B. Perkins· 1 shared C. Bonifant· 1 shared C. Esteb· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Fearnow

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Engineering CAR-NK cells to secrete IL15 sustains their anti-AML functionality, but is associated with systemic toxicities

I. Christodoulou, W. J. Ho, A. Marple, J. W. Ravich, A. Tam, R. Rahnama, A. Fearnow, C. Rietberg, S. Yanik, E. E. Solomou, R. Varadhan, M. A. Koldobskiy, C. L. Bonifant

This study shows that engineering NK cells to secrete IL15 improves their anti-AML activity but causes systemic toxicities.

bioRxiv · Sep 23, 2021 · PreprintImmunology

The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia

T. KARANTANOS, P. Teodorescu, B. Perkins, I. Christodolou, C. Esteb, R. Varadhan, E. Helmenstine, T. Rajkhowa, B. Paun, C. Bonifant, W. B. Dalton, L. P. Gondek, A. R. Moliterno, M. J. Levis, G. Ghiaur, R. J. Jones

This study identifies CCRL2 as a mediator of MDS and secondary acute myeloid leukemia growth through JAK2/STAT signaling, with potential therapeutic implications.

bioRxiv · Jul 29, 2021Cancer Biology