Author

C. L. Bonifant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. C. Johnston· 1 shared A. Fearnow· 1 shared A. Forjaz· 1 shared A. L. Kiemen· 1 shared A. Marple· 1 shared A. Tam· 1 shared C. C. Lee· 1 shared C. Rietberg· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. C. Johnston

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors

A. C. Johnston, G. M. Alicea, C. C. Lee, P. V. Patel, E. A. Hanna, E. Vaz, A. Forjaz, Z. Wan, P. R. Nair, Y. Lim, T. Chen, W. Du, D. Kim, T. D. Nichakawade, V. W. Rebecca, , D. Wirtz

This paper develops velocity receptors (VRs) to enhance CAR T cell migration through solid tumors, improving tumor infiltration and survival.

bioRxiv · Dec 13, 2023 · PreprintImmunology

Engineering CAR-NK cells to secrete IL15 sustains their anti-AML functionality, but is associated with systemic toxicities

I. Christodoulou, W. J. Ho, A. Marple, J. W. Ravich, A. Tam, R. Rahnama, A. Fearnow, C. Rietberg, S. Yanik, E. E. Solomou, R. Varadhan, M. A. Koldobskiy, C. L. Bonifant

This study shows that engineering NK cells to secrete IL15 improves their anti-AML activity but causes systemic toxicities.

bioRxiv · Sep 23, 2021 · PreprintImmunology