Author

Paige M. Lemen

University of CincinnatiORCID 0000-0002-1774-0385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:rat· 3 Approach:experimental assay· 2 Approach:Bayesian inference· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Evelin M. CotellaiD· 2 shared James P. HermaniD· 2 shared Maureen E. Fitzgerald· 2 shared Rachel D. MoloneyiD· 2 shared Susan E. Martelle· 2 shared Alexander Samir HatoumiD· 1 shared Arpana Agrawal AiD· 1 shared Aynara C. WulsiniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Evelin M. CotellaORCID

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3 papers

Recent·Most cited

Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

Paige M. Lemen, Yanning Zuo, Alexander Samir Hatoum, Price E. Dickson, Guy Mittleman, Arpana Agrawal A, Benjamin C. Reiner, Wade H. Berrettini, David George Ashbrook, Mustafa Hakan Gunturkun, Xusheng Wang, Megan K. Mulligan, Caleb J. Browne, Eric J. Nestler, Francesca Telese, , Hao Chen

This study identifies time-dependent epistatic interactions between Oprm1 and Fgf12 that modulate opioid-induced locomotion in mice and links Fgf12 to opioid behavior in humans.

eLife · Jul 29, 2026Peer-reviewedGenetics

Adolescent Stress Confers Resilience to Traumatic Stress Later in Life: Role of the Prefrontal Cortex

Evelin M. Cotella, Nawshaba Nawreen, Rachel D. Moloney, Susan E. Martelle, Kristen M. Oshima, Paige M. Lemen, Jordan N. NiBlack, Reetu R. Julakanti, Maureen E. Fitzgerald, Mark L. Baccei, James P. Herman

This study shows that adolescent stress can reduce the negative effects of traumatic stress in adulthood, with sex-specific changes in brain regions involved in fear responses.

Biological Psychiatry Global Open Science · Mar 7, 2022Peer-reviewedNeuroscience

Selective modulation of the glucocorticoid receptor with CORT108297 during chronic adolescent stress evokes sex specific effects in adulthood.

Evelin M. Cotella, Rachel L. Morano, Aynara C. Wulsin, Susan E. Martelle, Paige M. Lemen, Maureen E. Fitzgerald, Benjamin A. Packard, Rachel D. Moloney, James P. Herman

This study examines how adolescent chronic stress affects behavior and physiology differently in male and female rats, with GR signaling playing a role in some outcomes.

bioRxiv · May 24, 2019 · PreprintNeuroscience