Author

Raffaella Magnoni

Orphazyme (Denmark)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adrienne W. PatoniD· 1 shared Ana Paula Cordeiro· 1 shared Andrea DardisiD· 1 shared Brian ChristenseniD· 1 shared Bruno BembiiD· 1 shared Carsten ScaveniusiD· 1 shared Cathrine K. FogiD· 1 shared Cecilie L. SøltoftiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Adrienne W. PatonORCID

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Author profile →

2 papers

Recent·Most cited

Arimoclomol as a potential therapy for neuronopathic Gaucher Disease

Cathrine K. Fog, Paola Zago, Erika Malini, Lukasz M. Solanko, Paolo Peruzzo, Claus Bornæs, Raffaella Magnoni, Nikolaj H.T. Petersen, Bruno Bembi, Andrea Dardis, Thomas Kirkegaard

This study shows arimoclomol improves GCase function in GD models by enhancing its folding, maturation, activity, and localization.

bioRxiv · Mar 15, 2018 · PreprintNeuroscience

Intermolecular Disulfide-Bond Formation In Human FICD Modulates The Activity Of The Hyperactive E234G Mutant

Raffaella Magnoni, Minttu S. Virolainen, Celeste Menuet Hackney, Cecilie L. Søltoft, Ana Paula Cordeiro, Yun Liu, Carsten Scavenius, Jan J. Enghild, Brian Christensen, James C. Paton, Adrienne W. Paton, Esben Skipper Sørensen, Lars Ellgaard

This paper shows that FICD's adenylyltransferase activity induces ER stress and that its disulfide-bond formation modulates its activity in the context of a hyperactive mutant.

bioRxiv · Apr 11, 2017 · PreprintMolecular Biology