Structural basis of RNA Polymerase III transcription repression by Maf1
Matthias K. Vorländer, Florence Baudin, Robyn D. Moir, René Wetzel, Wim J. H. Hagen, Ian M. Willis, Christoph W. Müller
The paper presents a cryo-EM structure of yeast Maf1 bound to Pol III, revealing how Maf1 represses transcription by sequestering initiation elements and blocking the active site.
Nature Structural & Molecular Biology · Feb 17, 2020Peer-reviewedMolecular Biology