Florence Baudin

The paper investigates how Fpt1 is recruited to tRNA genes in budding yeast, revealing a dual role of TFIIIB and TFIIIC in its binding under different RNAPIII conditions.

This study uses cryo-EM and smFRET to reveal structural and kinetic details of yeast TFIIIC engagement with tRNA promoter DNA motifs.

The paper determines the structure of UAF bound to DNA and TBP to reveal how UAF selects RNA Polymerase I for ribosome biogenesis and mediates specific protein-DNA interactions.

The paper reports high-resolution cryo-EM structures of human RNA polymerase I, revealing structural features and disease-related mutations.

The paper identifies the molecular mechanism by which vault RNA1-1 regulates p62 oligomerisation, essential for selective autophagy.

The paper presents cryo-EM structures of human RNA polymerase III in unbound and transcribing states, revealing structural insights into its function and disease associations.

The paper presents a cryo-EM structure of yeast Maf1 bound to Pol III, revealing how Maf1 represses transcription by sequestering initiation elements and blocking the active site.