Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HSNCC
Khalid N.M. Abdelazeem, Diemmy Nguyen, Sophia Corbo, Laurel B. Darragh, Mike W. Matsumoto, Benjamin Van Court, Brooke Neupert, Justin D. Yu, Nicholas A. Olimpo, Douglas Grant Osborne, Jacob Gadwa, Richard B. Ross, Alexander T. Nguyen, Shilpa Bhatia, Mohit Kapoor, , Sana D. Karam
This study shows that targeting the EphB4-ephrinB2 axis with engineered ligands reduces metastasis in HNSCC by modulating tumor microenvironment and immune responses.
Oncogene · Nov 3, 2024Peer-reviewedCancer Biology