Laurel B. Darragh

Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

This study shows that combining immunotherapies can lead to divergent tumor responses based on the tumor microenvironment, with Treg depletion reversing progression in pancreatic cancer.

Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HSNCC

This study shows that targeting the EphB4-ephrinB2 axis with engineered ligands reduces metastasis in HNSCC by modulating tumor microenvironment and immune responses.

The pro-tumoral and anti-tumoral roles of EphA4 on T regulatory cells and tumor associated macrophages during HNSCC tumor progression.

This study investigates the dual role of EphA4 in T regulatory cells and tumor-associated macrophages during HNSCC progression, showing pro-tumoral and anti-tumoral effects respectively.