Pearling Drives Mitochondrial DNA Nucleoid Distribution
Juan C. Landoni, Matthew Domenic Lycas, Josefa Macuada, Willi L. Stepp, Roméo Jaccard, Christopher John Obara, Andrew S. Moore, David P. Hoffman, Jennifer Lippincott‐Schwartz, Wallace F. Marshall, Gabriel Sturm, Suliana Manley
The paper shows that mitochondrial DNA nucleoid distribution is controlled by pearling and cristae structure, revealing a mechanism for nucleoid spacing and segregation.
Science · Apr 2, 2026Peer-reviewedCell Biology