Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation
David Guerrero‐Gómez, José Antonio Mora-Lorca, Beatriz Sáenz‐Narciso, Francisco José Naranjo-Galindo, Fernando Muñoz-Lobato, Cristina Parrado‐Fernández, Julen Goikolea, Ángel Cedazo-Mı́nguez, Christopher D. Link, Christian Néri, María Dolores Sequedo, Rafael P. Vázquez‐Manrique, Elena Fernández-Suárez, Veit Goder, Roser Pané, , Antonio Miranda‐Vizuete
This study shows that loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation in C. elegans and other organisms.
Cell Death and Differentiation · Feb 15, 2019Peer-reviewedGenetics