Francisco José Naranjo-Galindo

This study shows that NTHL1 loss increases mtDNA copy number and mitochondrial function, enhancing cellular resilience to oxidative stress through stress response pathways.

This paper designs IL2 muteins with enhanced Treg or CD8 T cell specificity and improved production by predicting mutations using SolubiS and testing their functional and structural properties.

This study shows that loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation in C. elegans and other organisms.