Author

Ruochen Guo

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Chunlong XuiD· 1 shared Chunyi HuiD· 1 shared Guoling LiiD· 1 shared Hainan ZhangiD· 1 shared Hui YangiD· 1 shared Huimin DuaniD· 1 shared Ningyang Yuan· 1 shared Qian Peng· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Chunlong XuORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SRSF2 is a key player in orchestrating the directional migration and differentiation of MyoD progenitors during skeletal muscle development

Rula Sha, Ruochen Guo, Huimin Duan, Qian Peng, Ningyang Yuan, Zhenzhen Wang, Zhigang Li, Zhiqin Xie, Xue You, Ying Feng

This study shows SRSF2 is essential for MyoD progenitor migration and differentiation in skeletal muscle development, with effects mediated through gene regulation and alternative splicing.

eLife · Jun 3, 2024Peer-reviewedDevelopmental Biology

Engineering transposon-associated TnpB-1 ωRNA system for efficient gene editing and disease treatment in mouse

Zhifang Li, Ruochen Guo, Xiao-Zhi Sun, Guoling Li, Yuanhua Liu, Xiaona Huo, Rongrong Yang, Zhuang Shao, Hainan Zhang, Weihong Zhang, Xiaoyin Zhang, Shuangyu Ma, Yinan Yao, Xinyu Liu, Hui Yang, , Chunlong Xu

This paper engineers a TnpB-ωRNA system for efficient gene editing in mice, showing improved activity over Cas12f1 and successful disease prevention in a tyrosinaemia model.

bioRxiv · Jun 29, 2023 · PreprintMolecular Biology