Author

S. A. Barritt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. J. Butler· 1 shared A. M. Moon· 1 shared A. P. Davenport· 1 shared A. Simeonov· 1 shared A. W. Lohse· 1 shared B. A. Garcia· 1 shared C. A. LeClair· 1 shared C. C. Dibble· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. J. Butler

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Author profile →

2 papers

Recent·Most cited

Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors

M. C. Crawford, D. R. Tripu, S. A. Barritt, Y. Jing, D. Gallimore, S. C. Kales, N. V. Bhanu, Y. Xiong, Y. Fang, K. A. T. Butler, C. A. LeClair, N. P. Coussens, A. Simeonov, B. A. Garcia, C. C. Dibble, J. L. Meier

This study compares the biochemical and biological potencies of three EP300/CREBBP acetyltransferase inhibitors and demonstrates their utility in investigating epigenetic mechanisms.

bioRxiv · May 15, 2023Biochemistry

FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome

T. Brevini, M. Maes, G. J. Webb, W. T. H. Gelson, S. Forrest, P. Mlcochova, S. Dillon, S. Varankar, M. Darvish-Damavandi, V. L. Mulcahy, R. E. Kuc, T. L. Williams, V. Galanakis, M. Vila-Gonzalez, O. C. Tysoe, , F. Sampaziotis

This study shows FXR inhibition lowers ACE2 expression, reduces SARS-CoV-2 infection, and correlates with better clinical outcomes in COVID-19.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology