S. A. Mallal

PINK1 is a target of T cell responses in Parkinson's disease

The paper identifies PINK1 as an autoantigen targeted by T cells in Parkinson's disease, with reactivity predominantly observed in male patients.

Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.

The paper uses multiomic single-cell sequencing to analyze SJS/TEN patients' skin and blister fluid, identifying tissue-specific immune responses and T-cell clonotypes involved in pathogenesis.

CD3+ T-cell: CD14+monocyte complexes are dynamic and increased with HIV and glucose intolerance

The paper identifies increased CD3+ T-cell:CD14+ monocyte complexes in diabetes and HIV, associated with inflammation and metabolic changes.

CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

This study identifies CD4+CCR6+ T cells as key drivers of the BCG-induced transcriptional response, showing similar immune signatures across individuals.

Digital spatial profiling of coronary plaques from persons living with HIV reveals high levels of STING and CD163 in macrophage enriched regions

The paper uses digital spatial profiling to analyze coronary plaques from HIV-positive and HIV-negative individuals, finding higher CD163 and STING expression in HIV-positive plaques.