Author

S. A. Sonar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

B. J. LaFleur· 2 shared C. P. Coplen· 2 shared M. Jergovic· 2 shared B. A. Bixby· 1 shared C. Bime· 1 shared C. C. Weinkauf· 1 shared D. Bhattacharya· 1 shared G. D. Sempowski· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

B. J. LaFleur

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3 papers

Recent·Most cited

RORyt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system

S. A. Sonar, T. H. Metei, S. Inamdar, N. Lenka, G. Lal

This study shows that RORyt+CD4+ T cells promote IL-23R-mediated neuronal apoptosis in the CNS through IL-23 signaling, contributing to EAE.

bioRxiv · Apr 17, 2023 · PreprintImmunology

T-cell cellular stress and reticulocyte signatures, but not loss of naive T lymphocytes, characterize severe COVID-19 in older adults

M. Jergovic, M. Watanabe, R. Bhat, C. P. Coplen, S. A. Sonar, R. Wong, Y. Castaneda, L. Davidson, M. Kala, R. C. Wilson, H. L. Twigg, K. Knox, H. E. Erickson, C. C. Weinkauf, C. Bime, , J. Z. Nikolich

The paper identifies T-cell stress and reticulocyte signatures as markers of severe COVID-19 in older adults, while showing naive T-cell decline is age-related, not disease-specific.

bioRxiv · Dec 21, 2022Immunology

Early age-related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging

S. A. Sonar, J. L. Uhrlaub, C. P. Coplen, G. D. Sempowski, J. A. Dudakov, M. R. M. van den Brink, B. J. LaFleur, M. Jergovic, J. Nikolich-Zugich

This study shows that skin-draining lymph nodes atrophy early in mice, leading to impaired immune function and reduced effector cell production in older age.

bioRxiv · Nov 22, 2021Immunology