Author

S. Adler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. J. Winton· 2 shared F. Perrone· 2 shared M. Zilbauer· 2 shared N. Skoufou-Papoutsaki· 2 shared R. Kemp· 2 shared S. Mehmed· 2 shared A. N. Alilin· 1 shared A. Russell· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

D. J. Winton

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PTEN and ARID1A haploinsufficiency equip colonic epithelium for oncogenic transformation

N. Skoufou-Papoutsaki, S. Adler, S. Mehmed, C. Tume, C. Olpe, E. Morrissey, R. Kemp, A.-C. Girard, E. B. Moutin, C. S. R. Chilamakuri, J. L. Miller, C. Lindskog, F. Werle, K. Marks, F. Perrone, , D. J. Winton

The paper investigates how PTEN and ARID1A haploinsufficiency in colonic epithelium contributes to oncogenic transformation by altering clone dynamics and creating a pro-tumorigenic microenvironment.

bioRxiv · Mar 27, 2024 · PreprintCancer Biology

Metabolic and imaging phenotypes associated with RB1 and TP53 loss in prostate cancer

F. Ahmad, M. White, K. Yamamoto, D. R. Crooks, S. Agarwal, Y. Yang, B. Capaldo, S. Raj, A. N. Alilin, A. Ton, S. Adler, J. Seidel, C. Olkowski, M. K. Cherukuri, P. L. Choyke, , J. R. Brender

This study investigates metabolic and imaging phenotypes in prostate cancer linked to RB1 and TP53 loss, finding metabolic changes that may inform multimodal imaging strategies.

bioRxiv · Nov 15, 2023Cancer Biology

Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR

N. Skoufou-Papoutsaki, S. Adler, P. D'Santos, L. Mannion, S. Mehmed, R. Kemp, A. Smith, F. Perrone, K. Nayak, A. Russell, M. Zilbauer, D. J. Winton

This study develops an efficient ribonucleoprotein-based CRISPR method for editing human intestinal organoids, achieving 98% editing efficiency with no off-target effects and revealing PTEN loss phenotypes.

bioRxiv · Mar 31, 2023 · PreprintCell Biology