Author

B. Capaldo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. N. Alilin· 2 shared K. Kelly· 2 shared S. Agarwal· 2 shared A. Grayson· 1 shared A. Ton· 1 shared B. Gryder· 1 shared C. Olkowski· 1 shared D. J. VanderWeele· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. N. Alilin

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2 papers

Recent·Most cited

Metabolic and imaging phenotypes associated with RB1 and TP53 loss in prostate cancer

F. Ahmad, M. White, K. Yamamoto, D. R. Crooks, S. Agarwal, Y. Yang, B. Capaldo, S. Raj, A. N. Alilin, A. Ton, S. Adler, J. Seidel, C. Olkowski, M. K. Cherukuri, P. L. Choyke, , J. R. Brender

This study investigates metabolic and imaging phenotypes in prostate cancer linked to RB1 and TP53 loss, finding metabolic changes that may inform multimodal imaging strategies.

bioRxiv · Nov 15, 2023Cancer Biology

Targeting the PI3K/AKT pathway overcomes enzalutamide resistance by inhibiting induction of the glucocorticoid receptor

R. M. Adelaiye-Ogala, B. Gryder, Y. T. M. Nguyen, A. N. Alilin, A. Grayson, K. H. Jansson, M. L. Beshiri, S. Agarwal, B. Capaldo, J. A. Rodriguez-Nieves, K. Kelly, D. J. VanderWeele

This study shows that inhibiting the PI3K/AKT pathway blocks GR induction and overcomes enzalutamide resistance in prostate cancer by remodeling chromatin and enhancing AR activity.

bioRxiv · Oct 1, 2019Cancer Biology